Monday, February 28, 2011

Q: Beside Erectile Dysfunction and Pulmonary Hypertension , Sildenafil (Viagra) can be use for treatment in which other disease processes?


Answer: Altitude sickness and Jet lag recovery

Sildenafil has shown to be effective in prevention and treatment of high-altitude pulmonary edema mostly suffered by mountain climbers 1,2. Also some research papers shows that it may help in recovering Jet lag time 3.



References:

1. Richalet JP, Gratadour P, Robach P, et al. (2005). "Sildenafil inhibits altitude-induced hypoxemia and pulmonary hypertension". Am. J. Respir. Crit. Care Med. 171 (3): 275–81.

2. Perimenis P (2005). "Sildenafil for the treatment of altitude-induced hypoxaemia". Expert Opin Pharmacother 6 (5): 835–7.

3. Agostino, P. V.; Agostino PV, Plano SA, Golombek DA (2007). "Sildenafil accelerates reentrainment of circadian rhythms after advancing light schedules". Proc. Natl. Acad. Sci. U.S.A. 104 (23): 9834–9.